Ever sit back mid-session and wonder, “What’s actually happening in my body right now?” You’re not alone. Cannabis may feel magical, but there’s a ton of science behind the chill vibes, the munchies, or that sudden urge to reorganize your living room at 2 a.m. In this blog, we’re pulling back the curtain to explore how cannabis interacts with your body on a molecular level.
We’ll break down the role of your endocannabinoid system (yes, you have one!), how THC and CBD work their magic, and what really gives your favorite strain its unique kick. Let’s geek out together!
The Endocannabinoid System (ECS): Your Body’s Built-In Cannabis Receptor
The endocannabinoid system (ECS) is a critical part of your body that helps maintain balance in things like mood, sleep, appetite, and pain. It’s made up of three main components: receptors, endocannabinoids (naturally occurring compounds your body produces), and enzymes that help break everything down when it’s no longer needed.
There are two main types of receptors in the ECS:
- CB1 receptors: Found mostly in the brain and central nervous system, these receptors are responsible for the effects we associate with THC, like euphoria and appetite stimulation.
- CB2 receptors: Found primarily in the immune system, these receptors play a role in managing inflammation and other immune responses.
THC and Its Effects: The High and Beyond
THC is the cannabinoid most people know for one reason: it’s the one that gets you high. But how does it actually create that buzz? It all comes down to its interaction with the ECS, specifically the CB1 receptors in your brain.
THC and CB1 Receptors
When THC binds to these receptors, it triggers a cascade of effects that can leave you feeling euphoric, relaxed, or even a little giggly. This interaction is what drives the signature “high” associated with cannabis.
THC and Its Effect on the Brain
A key part of THC’s effect is the release of dopamine, the brain’s natural “feel-good” chemical. THC enhances dopamine levels, creating feelings of happiness and carefree relaxation that many users enjoy.
Beyond the High—Other Effects of THC
THC also affects other areas of the brain, influencing appetite (hello, munchies), memory, and even motor skills—which is why you shouldn’t drive after using it.
It’s important to remember that THC’s effects can vary based on a few factors:
- Consumption method: Smoking or vaping produces faster effects, while edibles take longer but last longer.
- Tolerance: Regular use can make your body less sensitive to THC.
- Biology: Everyone’s ECS is unique, so the same dose might hit people differently.
- Dose: The higher the dose of THC that you consume, regardless of other factors, the more pronounced its effects will be. Start low and go slow – build up to your preferred dose slowly through careful experience.
CBD: The Non-Psychoactive Master of Mellow
Unlike THC, CBD doesn’t bind directly to ECS receptors, which means it won’t get you high. Instead, CBD indirectly influences CB1 and CB2 receptors, supporting the ECS in maintaining balance.
CBD’s Balancing Effects
One of CBD’s standout roles is modulating THC’s effects by:
- Potentially toning down THC’s intensity, which is why some products combine the two cannabinoids for a more balanced experience.
On its own, CBD has plenty of potential benefits, like:
- Promoting relaxation.
- Reducing inflammation.
- Helping manage stress or discomfort.
Because it doesn’t interact with CB1 receptors in the same way THC does, CBD won’t give you a buzz. What it can do is offer a sense of calm and physical relief, making it a popular choice for those looking for the therapeutic benefits of cannabis without the high.
Terpenes & the Entourage Effect
Terpenes are the aromatic compounds in cannabis that give each strain its distinct scent and flavor. That piney, citrusy, or floral aroma? All thanks to terpenes. They aren’t exclusive to cannabis, either. You’ll find them in everyday plants like lavender, citrus fruits, and even pine trees.
But terpenes aren’t just about smell. They also play an important role in how cannabis affects your body in a phenomenon called the Entourage Effect. The entourage effect is the idea that cannabinoids (like THC and CBD) and terpenes work together to create a unique experience. Essentially, the combination of these compounds enhances their individual effects.
For example, myrcene, a terpene with an earthy aroma, may enhance THC’s ability to relax you. On the other hand, limonene, which has a bright citrusy scent, is known for its uplifting and mood-boosting properties. Together with cannabinoids, terpenes help fine-tune how each strain makes you feel, whether it’s calm and cozy or energized and creative.
Consumption Methods and Their Impact on the Body
How you consume cannabis has a huge impact on how it affects your body. Each method has a different level of absorption and bioavailability (how much of the cannabinoids your body can actually use). This affects how quickly you feel the effects and how long they stick around.
Here’s a quick breakdown:
- Smoking & Vaping: These methods have the fastest onset. You’ll feel the effects within minutes, but they only last a couple of hours. This is because cannabinoids are absorbed directly through your lungs into your bloodstream, giving you that rapid onset.
- Edibles: Unlike smoking or vaping, these take a while to kick in (typically 30 minutes to 2 hours). But, the effects last much longer, sometimes up to 8 hours or more. That’s because your liver processes the cannabinoids, creating a long-lasting experience.
- Sublinguals & Tinctures: When placed under your tongue, these drops offer faster effects than edibles, often within 15 to 30 minutes. They also bypass your digestive system, which means more cannabinoids make it into your bloodstream.
- Topicals: Topicals don’t enter the bloodstream, so you won’t feel psychoactive effects. They’re applied directly to the skin and are great for localized relief, like soothing sore muscles or joints.
Discover More: The Science of Cannabis Awaits on Aura’s Blog
Cannabis does a lot more than just make you feel good—it works in harmony with your body’s natural systems to create unique effects tailored to you. From the endocannabinoid system to the role of terpenes and your choice of consumption methods, there’s a lot going on behind the scenes to shape your experience.
Want to keep learning? Dive deeper into the world of cannabis with Aura’s blog! The Weed Feed has got plenty of tips, guides, and insights to help you make the most of your cannabis journey.
The contents of this blog are intended for informational purposes only. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition.